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Complement component 4 : ウィキペディア英語版 | Complement component 4
Complement component 4 is a protein involved in the complement system. It is cleaved into proteins 4a and 4b; 4b can be further cleaved into 4c and 4d.〔http://www.immunologyreport.com/ATC2013/pdf/MacConmara.pdf〕 * C4a is an anaphylatoxin. * C4b forms part of C3-convertase, in conjunction with 2a: * C4b can bind CR1. ==Clinical significance== It is responsible for the Chido Rodgers blood group system.〔(Chido Rodgers blood group system at BGMUT ) Blood Group Antigen Gene Mutation Database at NCBI, NIH〕 C4d has been identified as a biomarker for systemic lupus erythematosus.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Complement component 4」の詳細全文を読む
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